Right from its inception, the institute has executed many research schemes and
programmes. The research activities are related mainly to two areas
·
Development of New Vaccines in the Biologicals production against common
animals diseases and improvement in Vaccine production technology.
·
Diagnosis and study of animal diseases and their epidermiology for purposes of
disease monitoring surveillance and forecasting.
Disease Investigation Sections:
This
division consists of the Central Disease Investigation Laboratory located
at Bangalore, there are 9 Regional Animal Disease Diagnostic
Laboratory (ADD & IC) located at Belgaum, Bellary, Gulbarga, Davangere,
Mysore, Mangalore, Shimoga, Bidar and wild animal disease diagnostic laboratory
located at BNP, Bannerghatta, Bangalore. The ADD & IC have jurisdiction of
3-5 districts ADD & IC provide diagnostic service and cold storage facility
for storing and supply of vaccines produced by the Institute. The ADD & IC
are looked after by Regional Research Officers (RROs). ADD & IC also act as
Information Centers for KVAFSU.
Research
The following are the ongoing
research projects funded by different agencies at the Institute.
|
|
Project
|
Funding
|
|
1
|
Southern
Regional Disease Diagnostic Laboratory (SRDDL)
|
GOI
(100%)
|
|
2
|
All
India Co-ordinated Research Project on Foot and Mouth Disease (AICRP on FMD)
|
ICAR
GOK (75%) (25%)
|
|
3
|
Assistance
to states for Control of Animal Diseases (ASCAD)
|
GOI
GOK (75%) (25%)
|
|
4
|
National
Project on Rinderpest Eradication (NPRE)
|
GOI
(100%)
|
|
5
|
All
India Co-ordinated Research Project on Animal Disease Monitoring and
Surveillance (Collaborating Unit)
|
ICAR
(100%)
|
|
6
|
All
India Network Project on Blue Tongue Disease in Sheep
|
ICAR (100%)
|
|
7
|
DBT
|
DBT (100%)
|
|
8
|
Leptospira
|
ICAR (100%)
|
COMPLETED / ONGOING RESEARCH PROGRAMMES:
1.
Epidemiology of Foot and Mouse Disease (ICAR,1977)
2.
Use of synthetic dehydrated media in the production of vaccines.
3.
Tissue culture sheep pox-using lamb testis cells was carried out in
Collaboration with the department of the veterinary Microbiology, University
of Agricultural Sciences. The newly developed vaccine has given
satisfactory protection under field conditions.
4.
The following studies on parthenium hysterophorus a weed associated
with human allergy,were completed in collaboration with Indian Institute
of Science.
·
Isolation, Identification and characterisation of parthenium, the toxic
principle of parthenium plant.
·
Pathology of the toxic effects of parthenium in epidermental and natural
situations -haematology ,gross and histopathology, clinical chemistry and
immunological aspects.
·
The biochemical effects of the toxin in cell culture systemic using labelled
compounds.
·
Detoxification and utilisation of parthenium as feed supplement to livestock
and poultry.
·
The effect of parthenium, a sesquiterpene compound as an anticancerous agent.
5. Behavour of Rinderpest virus of sheep origin.
· Transmission
of RP virus isolated from sheep to cattle & vice- versa.
·
Change
in the pattern of RP virus in affecting sheep & cattle.
6.
Prevalence of birth defects of animals as models to study human birth defects.
Wild
life diseases:
1.
Rabies in elephants & leopard, HS & Anthrax in Bison and Elephants, RP
in Bisons, Theileriasis & Babesiosis in Bisons, Trypanosomiasis
in captiv & wildfelines. Studies on Epidemiology of Blue Tongue disease in
sheep and molecular characteriztion of blue tongue virus (sponsored by
Karnataka Sheep & Sheep products Development board).
2.
Development of DNA
based diagonostics for diagnosis of leptospirosis.
3.
AICIRP on Animal Disease Monitoring and Surveillance (Regional Research Unit).
4.
Seroprevalence of trypanosomiasis in cattle and wild felines in karnataka.
5.
Production of Lasota vaccine.-1998 Test batch.
6.
Production of IBD vaccine.-1996-97 adapted to chicken embryos.
7.
Production of Tissue culture live sheep pox vaccine 2004.
8.
Production of Tissue culture Rabis vaccine using BHK cell line.
9.
Production of multiple emulsion HS vaccine.
10.
Production of HS & BQ combined alum precipitated vaccine -trial 1997.
11.
Freeze Dried ET toxioid -Trial Batch 1997.
12.
Studies on Avian Mycoplasmosis -Trial Batch June 2000.
13.
Bluetongue inactivated vaccine ( polyvalent ) - under trail.
TRAINING:
1.
The Institute is organising training programme in Animal Disease Diagnosis for
Veterinarians from state Diagnostic Laboratories and also for Veterinarians
from other state.
2. The
internship training programmes are conducted for BVSc, Students for Veterinary
College, Bangalore and Bidar.
3.
Postgraduate students from other Universities are also given training in
specified areas.
4.
Training facilities are provided at the Institute in Animal Health Coverage,
disease diagnosis and biological production.
·
To impart various aspects of animal health coverage to diary and poultry
farmers, rural development agencies ,social workers, rural youth centers and
members of voluntary organisations.
·
To Veterinary technical personnel of the state.
·
To Veterinary Officers of the state ,in charge of hospitals and Government
livestock and poultry farms, various aspects of diagnosis, prevention and
control methods of animal diseases. Similar programmes are included for
Veterinary, Management banking, Insurance & other professionals at state
and national level.
·
The internship training programmes are conducted for BVSc, Students for
Veterinary College, Bangalore and Bidar.
·
Post graduate students from other Universities are also given training in
specified areas.
FUTURE
PLANS AND EXPANSION PROGRAMMES:
The
future plans and expansion programmes of the institute are so envisaged as to
include introduction of innovative technologies in the production of vaccines
and diagnostics as well as to enhance the range of veterinary biologicals with
a view to greatly reduce the economic losses to the farmer and make the state
disease free zone if not total eradication. These programmes include:
1. Usage
of fermenter technology for large scale production of bacterial vaccines.
2. Use
of recombinant DNA technology for production of diagnostic antigens and kits.
3. Development
of new generation vaccines.
4. Production
of specific monoclonal antibodies for the development of diagnostic kits for
speedy diagnosis.
5. Development
of facilities for training and initiating large-scale seriological / molecular
epidemiological studies to combat animal diseases.
6. Development
of animal disease animal health extension education programmes for better
control and prevention of animal diseases to enhance rural economy.
7.
Use of fermentation technology of cell culture based vaccines.